4th Core Group Meeting. COST Action 17112 PRO-EURO DILI NET. 26th November 2020. 2.00-3.00 PM (GMT)
CA-17112 Management Committee updates & Working Groups meeting @ EASL Digital International Liver Congress 2020
Lectures. 29th August 2020.
Core Group Meetings (CGM)
Management Committee Meetings (MCM)
Working Group Meetings (WGM)
Plenary lectures. 2 WGs Meeting. Palermo, 10th October 2019
Reports from WGs Leaders: where do we stand now? 2 WGs Meeting. Palermo, 10th October 2019
Short presentations from WGs Leaders. 1 WGs Meeting. Málaga, 14 March 2019
Plenary lectures. 1 WGs Meeting. Málaga, 14 March 2019
2nd TRAINING COURSE, COST ACTION 17-112: RECENT ADVANCES ON STEM CELL RESEARCH AND CELL THERAPIES.
Lisbon, Portugal. 10th-11th October 2019
1st TRAINING COURSE, COST ACTION 17-112: ASSESSMENT OF DRUG-INDUCED LIVER INJURY: KEY RULES AND COMMON PITFALLS. HOW TO MAKE A CLINICAL NARRATIVE.
Recognition by EUROTOX as a Continuing professional development (CPD) course of 11 teaching hours.
Presentations
Grant beneficiaries & survey assessment
Short-Term Scientific Missions (STSMs). COST ACTION 17-112
- ECOST-STSM-Request-CA17112-48461. Establishment of iPSC differentiated to human hepatocyte knockouts.
*Participant: Alejandro Hionides. Universidad Complutense de Madrid (Madrid, Spain)
*Type of Mission: Clinical
*Location: University of Oslo, Sognsvannsveien 9, 0372 Oslo (Norway)
*Responsible: Dr Gareth John Sullivan. Email: g.j.sullivan@medisin.uio.no
*Dates: 2021-09-01 – 2021-10-31
- ECOST-STSM-Request-CA17112-48249. Advancing in vitro models of DILI: key techniques for the study of hepatotoxicity in cell cultures
*Participant: Daniel Enrique Di Zeo Sánchez. Biomedical Research Institute of Málaga (IBIMA) / University of Málaga (Málaga, Spain).
*Type of Mission: Clinical
*Location: Faculty of Pharmacy of the University of Lisbon
*Responsible: Joana Miranda. Email: jmiranda@ff.ul.pt
*Dates: 2021-07-01- 2021-07-31
- ECOST-STSM-Request-CA17112-48256
*Dates: 2021-09-01 – 2021-10-31
- ECOST-STSM-Request-CA17112-47460. DILI principles in detection, characterization, phenotyping, risk assessment and adjudication. Management of DILI databases. Pathophysiology, therapeutic strategies and new biomarkers in DILI using patient-derived dermal fibroblasts, keratinocytes and hep
*Participant: Lauryna Aukštikalnė. Lithuanian University of Health Sciences Institute of Physiology and Pharmacology (Kaunas)
*Type of Mission: Clinical
*Location: Universidad de Málaga (UMA), Málaga, Spain
*Responsible: Dr. María Isabel Lucena, lucena@uma.es
*Dates: 2021-01-11 – 2021-02-28
- ECOST-STSM-Request-CA17112-46009. Training in the use of HepaRGs and monitoring POR expression.
*Participant: Francisco Esteves. Faculdade de Ciências Médicas, UNL, Lisboa (Portugal).
*Type of Mission: Basic
*Location: Institute of Bioengineering, University of Edinburgh, Scotland (UK)
*Responsible: Dr. Leonard J. Nelson
*Dates: 01.03.2020-15.03.2020
- ECOST-STSM-Request-CA17112-46089. Methodology of systematic review of observational studies in DILI
*Participant: Cristiana Torres Freixo, Faculdade de Medicina. Universidade do Porto. Porto (Portugal)
*Type of Mission: Clinical
*Location: Nottingham Digestive Diseases Centre, Nottingham (UK)
*Responsible: Dr. Guruprasad Aithal
*Dates: 19.01.2020-05.02.2020
- ECOST-STSM-Request-CA17112-45167. ROLE OF NRF2 IN APAP-MEDIATED TOXICITY
*Participant: Nuria López-Alcántara (Spain)
*Type of Mission: Basic
*Location: Institute of Physics of the Czech Academy of Sciences, Prague (Czech Republic)
*Responsible: Dr. Oleg Lunov
*Dates: 02.12.2019-22.12.2019
- ECOST-STSM-Request-CA17112-45133. VIRAL AND AUTOIMMUNE HEPATITIS, CIRRHOSIS, ACUTE LIVER FAILURE, DILI, HILI INTRAHEPATIC CHOLESTASIS OF PREGNANCY
*Participant: Goran Bokan Faculty of medicine, Banja Luka, BA
*Type of Mission: Clinical
*Location: Internal Medicine & Hepatology, DIBIMIS, University of Palermo (Italy)
*Responsible: Dr. Anna Licata
*Dates: 30.09.2019-31.10.2019
- ECOST-STSM-Request-CA17112-45122. “SHORT TERM SCIENTIFIC MISSION” FOR THE LIVER FIBROSIS DIAGNOSIS THROUGH THE LIVER ELASTROGRAPHY.
*Participant: Enrique del Campo, UMA. Málaga (Spain)
*Type of Mission: Clinical
*Location: Internal Medicine & Hepatology, DIBIMIS, University of Palermo (Italy)
*Responsible: Dr. Anna Licata
*Dates: 10.07.2019-18.10.2019
Co-branding rules are important in order to acknowledge COST as the funding source.
2ND PROGRESS REPORT (PR2) OF THE COST ACTION 17112
NEWSLETTERS
The Management Committee has approved the ITC conference grant awarded to the PhD Student, Ms. Joana Saraiva (Portugal) with the purpose of her attendance for the EUROTOX congress 2019 hold in Helsinki (8-11 September).
Her abstract entitled: “Hepatocyte-like cells in microfluidic devices: a new platform for disease modelling, drug screening and toxicology”
(Abstract ID: 250), submitted as “Poster” has been accepted and selected one of the 5 top posters presentation. She has adquired new concepts in pre-clinical methods in DILI that undoubtedly will help her to successfully continue her research on the field of DILI.
In order to support young investigator ́s career development and to encourage interactions among the participants in the COST Action 17112, we are launching a New Insights: Young Investigators Seminar Series. We propose this as a series of talks, ONCE monthly, given by early career investigators (ECIs) – with the supervision of their tutors (both hosts and mentors). The outline of the session would be a brief introduction of the speaker by the mentor, a talk around 45 min with 15 min left for discussion. Conferences will be held the 3rd Thursday of each month at 16.30h (CET) starting from June 17.
Our next speakers will be Ismael Alvarez and Hao Niu from the Departments of Medicine and Pharmacology at Malaga University, IBIMA, who will be addressing an important topic on translational research in DILI
Clinical Trials and Drug-Induced Liver Injury: what have we learnt and where can we go.
As members of the working group on: Design and Endpoints in Clinical DILI Investigations and Trials, they have led a systematic review with meta-analysis on the treatment and prevention of DILI which may pave the way to set up an international multicentre research network to investigate the effectiveness of known and novel interventions that could improve clinical outcomes of DILI.
Date: 15th JULY, at 16.30h (CEST)
Guest: Ismael Alvarez, Hao Niu
Our first guest will be Nuria López-Alcántara who left Javier Cubero´s lab to enjoy a short term scientific-mission (STSM) in the laboratory of Oleg Lunov at the Institute of Physics in Prague (Czech Republic). She will narrate her experience and learning, will discuss the methods/ techniques used and what she aims to develop further in the future.
Date: 17th JUNE, at 16.30h (CET)
Guest: Nuria López-Alcántara